Acta Veterinaria Eurasia
Original Article

Clinicopathological Assessment of Infectious Bursal Disease Vaccine Using Phytogenic Mucoadhesive Agents in Challenged Broilers


Department of Veterinary Pathology, Faculty of Veterinary Medicine, University of Ibadan, Nigeria


Department of Veterinary Medicine, Pan African University, Life and Earth Sciences Institute(PAULESI), University of Ibadan, Nigeria

Acta Vet Eurasia 2020; 46: 75-80
DOI: 10.5152/actavet.2020.19020
Read: 62 Downloads: 26 Published: 13 January 2020

Loss occurring due to disharmonized vaccination against infectious bursal disease (IBD) has necessitated the use of plant gums in poultry production. This study evaluated the oral administration of IBD vaccine with equal proportions of Cedrela odorata and Khaya senegalensis in chickens. Two hundred and forty chicks were categorized into four groups, namely, mucilage-IBD vaccine (virus challenged) (GGVOR), IBD vaccine alone (virus challenged) (GVOR), mucilage alone (virus challenged) (GOR), and not vaccinated-no mucilage (virus challenged) (NVNG/C). The birds were clinically monitored after vaccination and infection; lymphoid tissues were taken from weak euthanized birds for gross and microscopic examinations. The clinical data and lesion scores from the tissues were analyzed and compared at α=0.05. All the birds were apparently healthy pre- and post-vaccinations. A few days post-infection, there were signs of pecking, soiling of the vents, and feathers with projectile yellowish diarrhea, with varied mortalities in the GOR and NVNG/G birds. The bursa of Fabricius, spleen, cecal tonsils, and Harderian gland were edematous, hyperplastic, hemorrhagic, and inflamed to various degree across the groups, but were very severe in the NVNG/C birds. No mortality was recorded in the GVVOR and GVOR groups. The administration of IBDV with Cedrela odorata and Khaya senegalensis gums clinically enhanced the birds against, IBD.

Cite this article as: Adeniran, G. A., Jarikre, T.A, Ola, O.O., Ohore, O.G., Oyebanji, V. O., Emikpe, B.O., 2020. Clinicopathological assessment of Infectious bursal disease vaccine using phytogenic mucoadhesive agents in challenged broilers. Acta Vet Eurasia.

ISSN2618-639X EISSN 2619-905X